Monoamine Oxidase and Dopamine β-Hydroxylase Inhibitors from the Fruits of Gardenia jasminoides
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چکیده
منابع مشابه
Monoamine Oxidase and Dopamine β-Hydroxylase Inhibitors from the Fruits of Gardenia jasminoides
This research was designed to determine what components of Gardenia jasminoides play a major role in inhibiting the enzymes related antidepressant activity of this plant. In our previous research, the ethyl acetate fraction of G. jasminosides fruits inhibited the activities of both monoamine oxidase-A (MAO-A) and monoamine oxidase-B (MAO-B), and oral administration of the ethanolic extract slig...
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Three new iridoids, Gardenal-I (1), Gardenal-II (2) and Gardenal-III (3), together with nine known iridoid glycosides; geniposide (4), 6-β-hydroxy geniposide (5), 6-α-hydroxy geniposide (6), 6-α-methoxy geniposide (7), feretoside (8), genipin-1-β-gentiobioside (9), shanzhiside (10), lamalbidic acid (11) and picrocrocinic acid (12) were isolated from EtOH extract of G. gasminoides. The structure...
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Iridoids are one of the most widely distributed secondary metabolites in higher plants. They are pharmacologically active principles in various medicinal plants and key intermediates in the biosynthesis of monoterpenoid indole alkaloids as well as quinoline alkaloids. Although most iridoids are present as 1-O-glucosides, the glucosylation step in the biosynthetic pathway has remained obscure. W...
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comparisons be possible. The real differences in surgical mortality that do exist between surgeons and centres may teach important lessons. One study compared mortality between a teaching hospital and its adjacent district hospital and led to a proper intensive care unit being provided in the district hospital. 14 The confidential inquiry into perioperative deaths emphasised the value of regula...
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Monoamine Oxidase Inhibitors DEAR SIR, Dr Pare's article on †̃¿ The Present Status of Monoamine Oxidase Inhibitors' is one of a genre that marks the renaissance of these drugs (Murphy et al, 1984; White & Simpson, 1985). This is understandable given that the †̃¿ second generation' compounds are less exciting than hoped, that early use of phenelzine was often with inadequate dosage and that im...
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ژورنال
عنوان ژورنال: Biomolecules and Therapeutics
سال: 2012
ISSN: 1976-9148
DOI: 10.4062/biomolther.2012.20.2.214